In biological neural networks, neurons transmit chemical signals through synapses, and there are multiple ion channels during transmission. Moreover, synapses are divided into inhibitory synapses and excitatory synapses. The firing mechanism of previous spiking neural P (SNP) systems and their variants is basically the same as excitatory synapses, but the function of inhibitory synapses is rarely reflected in these systems. In order to more fully simulate the characteristics of neurons communicating through synapses, this paper proposes a dynamic threshold neural P system with inhibitory rules and multiple channels (DTNP-MCIR systems). DTNP-MCIR systems represent a distributed parallel computing model. We prove that DTNP-MCIR systems are Turing universal as number generating/accepting devices. In addition, we design a small universal DTNP-MCIR system with 73 neurons as function computing devices.