The aim of the work is a comparison of two combustion systems of fuels with different reactivity. The first is combustion of the fuel mixture and the second is combustion in a dual-fuel engine. Diesel fuel was burned with pure ethanol. Both methods of co-firing fuels have both advantages and disadvantages. Attention was paid to the combustion stability aspect determined by COVIMEP as well as the probability density function of IMEP. It was analyzed also the spread of the maximum pressure value, the angle of the position of maximum pressure. The influence of ethanol on ignition delay time spread and end of combustion process was evaluated. The experimental investigation was conducted on 1-cylinder air cooled compression ignition engine. The test engine operated with constant rpm equal to 1500 rpm and constant angle of start of diesel fuel injection. The engine was operated with ethanol up to 50% of its energy fraction.