Tri-generation plants will have an important role in the near future in the residential sector where heating and cooling demands come into play throughout the year. Depending on the building’s location, the characteristics of its enclosure and its use, the thermal loads and demands will be different. This article analyses and compares a combined cooling, heating and power (CCHP) system tested in the laboratory and a single household located in Spain. The cooling capacity is obtained using a reversible heat pump where the compressor is driven directly by a gas engine with internal combustion engine (ICE) technology. The tests were carried out in a work bench at three different operating speeds. A variable-speed model is developed in the TRNSYS simulation environment with an operating strategy following the thermal load (FTL). Once the micro-CCHP system was modeled with experimental data and validated, it was dynamically simulated to analyze its performance in different climatic zones defined in the Spanish “Código Técnico de la Edificación” (CTE). This study reveals that the micro-CCHP system is suitable in mild weathers during the summer season.