In this work we propose a new hybrid model, a combination of the manifold learning Principal Components (PC) technique and the traditional multiple regression (PC-regression), for short and medium-term forecasting of daily, aggregated, day-ahead, electricity system-wide load in the Greek Electricity Market for the period 2004⁻2014. PC-regression is shown to effectively capture the intraday, intraweek and annual patterns of load. We compare our model with a number of classical statistical approaches (Holt-Winters exponential smoothing of its generalizations Error-Trend-Seasonal, ETS models, the Seasonal Autoregressive Moving Average with exogenous variables, Seasonal Autoregressive Integrated Moving Average with eXogenous (SARIMAX) model as well as with the more sophisticated artificial intelligence models, Artificial Neural Networks (ANN) and Support Vector Machines (SVM). Using a number of criteria for measuring the quality of the generated in-and out-of-sample forecasts, we have concluded that the forecasts of our hybrid model outperforms the ones generated by the other model, with the SARMAX model being the next best performing approach, giving comparable results. Our approach contributes to studies aimed at providing more accurate and reliable load forecasting, prerequisites for an efficient management of modern power systems.