Climate change policy and sustainable development issues and goals are closely intertwined. Recognizing the dual relationship between sustainable development and climate change points to a need for the exploration of actions that jointly address sustainable development and climate change. Technology transfer is considered an issue with growing interest worldwide and has been recognized as the key in supporting countries to achieve sustainable development, while addressing climate change challenges. This study presents an integrated decision support methodological framework for the formulation and evaluation of activities to promote technology transfer, as well as the provision of clear recommendations and strategies for framing specific policy in the context of climate change. The philosophy of the proposed approach, under the name: assess-identify-define (AID), consists of three components, where each one focuses on a particular problem. The methodology is integrated using appropriate tools in the information decision support system for effective technology transfer (DSS-ΕTT). The pilot application of the proposed methodology, in five representative developing countries, provided the possibility to evaluate the characteristics of the adopted methodology in terms of completeness, usability, extensionality, as well as analysis of results reliability.