LAPSE:2018.0338
Published Article
LAPSE:2018.0338
Optimal Control Strategy for TB-HIV/AIDS Co-Infection Model in the Presence of Behaviour Modification
Temesgen Debas Awoke, Semu Mitiku Kassa
July 31, 2018
A mathematical model for a transmission of TB-HIV/AIDS co-infection that incorporates prevalence dependent behaviour change in the population and treatment for the infected (and infectious) class is formulated and analyzed. The two sub-models, when each of the two diseases are considered separately are mathematically analyzed. The theory of optimal control analysis is applied to the full model with the objective of minimizing the aggregate cost of the infections and the control efforts. In the numerical simulation section, various combinations of the controls are also presented and it has been shown in this part that the optimal combination of both prevention and treatment controls will suppress the prevalence of both HIV and TB to below 3% within 10 years. Moreover, it is found that the treatment control is more effective than the preventive controls.
Keywords
behaviour change, dynamical systems, equilibrium, Human Immunodeficiency Virus (HIV), optimal control, stability, TB-HIV co-infection, treatment, tuberculosis (TB)
Suggested Citation
Awoke TD, Kassa SM. Optimal Control Strategy for TB-HIV/AIDS Co-Infection Model in the Presence of Behaviour Modification. (2018). LAPSE:2018.0338
Author Affiliations
Awoke TD: Department of Mathematics, Kotebe Metropolitan University, P.O. Box 31248, Addis Ababa, Ethiopia
Kassa SM: Department of Mathematics and Statistical Sciences, Botswana International University of Science and Technology (BIUST), P/Bag 16, Palapye, Botswana; Department of Mathematics, Addis Ababa University, P.O. Box 1176, Addis Ababa, Ethiopia [ORCID]
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Journal Name
Processes
Volume
6
Issue
5
Article Number
E48
Year
2018
Publication Date
2018-05-01
Published Version
ISSN
2227-9717
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PII: pr6050048, Publication Type: Journal Article
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LAPSE:2018.0338
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doi:10.3390/pr6050048
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Jul 31, 2018
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